Iodine → HCID 178506332, Verbindung

HRID 2243279

Reaktionsgleichung

Reaktionsgleichung von HRID 2243279
[F:1][C:2]([F:12])([C:7]1[CH:11]=[CH:10][NH:9][N:8]=1)[C:3]([F:6])([F:5])[F:4].[N+]([O-])([O-])=O.[NH4+].[Ce].[Ce].[I:20]I>C(#N)C>[I:20][C:11]1[C:7]([C:2]([F:1])([F:12])[C:3]([F:6])([F:5])[F:4])=[N:8][NH:9][CH:10]=1

Komponenten

5

Edukt 3

HCID 807IodineHCID 86617141Dicerium ammonium nitrateHCID 1785063263-(pentafluoroethyl)-1H-pyrazole

Produkt 1

HCID 178506332HCID 178506332, VerbindungAusbeute 162,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

An acetonitrile solution (20 ml) of 3-pentafluoroethyl-1H-pyrazole (2.0 g), dicerium ammonium nitrate (3.0 g) and iodine (1.6 g) was refluxed for 3 hours. After cooling, the reaction solution was washed with saturated aqueous solution of sodium thiosulfate and saturated aqueous solution of sodium chloride. After drying the organic layer with magnesium sulfate, the solvent was distilled off under the reduced pressure to obtain 4-iodo-3-pentafluoroethyl-1H-pyrazole (3.2 g).

Aufarbeitung

  1. temperatureAfter cooling
  2. washthe reaction solution was washed with saturated aqueous solution of sodium thiosulfate and saturated aqueous solution of sodium chloride
  3. dry with materialAfter drying the organic layer with magnesium sulfate
  4. distillationthe solvent was distilled off under the reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-616beeebfdde422abc9d876986fc83e7
Quelldatensatz
uspto-grants-2010_03
Patentnummer
US07674807B2

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