Thiourea → 5-(3-Methanesulphonyl-phenyl)-4-methyl-thiazol-2-ylamine hydrobromide

HRID 2247399Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2247399
[Br:1][CH:2]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12]([CH3:15])(=[O:14])=[O:13])[CH:7]=1)[C:3](=O)[CH3:4].[NH2:16][C:17]([NH2:19])=[S:18]>>[BrH:1].[CH3:15][S:12]([C:8]1[CH:7]=[C:6]([C:2]2[S:18][C:17]([NH2:19])=[N:16][C:3]=2[CH3:4])[CH:11]=[CH:10][CH:9]=1)(=[O:14])=[O:13]

Komponenten

3

Edukt 2

HCID 2723790ThioureaHCID 858616531-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

Produkt 1

HCID 865984455-(3-Methanesulphonyl-phenyl)-4-methyl-thiazol-2-ylamine hydrobromide

Versuchsvorschrift

A stirred solution of 1-bromo-1-(3-methanesulphonyl-phenyl)-propanone (176c) (0.32 g, 1.01 mmol) is treated with thiourea (0.067 g, 0.88 mmol) added in one portion. The reaction mixture is allowed to stir at room temperature over two days. The product precipitates out and is filtered to yield the title compound as while solid.

Aufarbeitung

  1. additionadded in one portion
  2. customThe product precipitates out
  3. filtrationis filtered

Quellen und Nachweise

ORD-Eintrag
ord-59f736901d8149fba120e1317130c35c
Quelldatensatz
uspto-grants-2010_03
Patentnummer
US07687637B2

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