HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzoyl Peroxide → 2-(Bromomethyl)-5-chlorobenzo[d]oxazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzoyl Peroxide | HCID 7187 | — |
| Edukt | 5-Chloro-2-methylbenzoxazole | HCID 29510 | — |
| Edukt | N-bromobutanimide | HCID 67184 | — |
| Lösungsmittel | Carbon Tetrachloride | HCID 5943 | — |
| Produkt | 2-(Bromomethyl)-5-chlorobenzo[d]oxazole | HCID 12745945 | — |
Reaktionsschritte
A solution of the benzoxazol (1.3 ) (Step 2) in CCl4 (15 mL) was treated with N-bromo-succinimide (NBS) (1.5 ) and benzoyl peroxide (38 mg) at reflux using a U.V. lamp for 24 hours. Filtration, evaporation, and flash chromatography of the residue using 1:1 hexane/toluene afforded the title compound which was used as such for the next step.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05037840 |
| Quelldatensatz | uspto-grants-1991_08 |
| ORD ID | ord-ff4e4791d10a445bbab656ba07c83a24 |
| Quellennotiz | uspto-grants-1991_08 |