Hydrogen Sulfide → HCID 14579136, Verbindung

Reaktionsgleichung

[SH2:1].C(O)C.[C:5]([CH:7]([C:17]1[O:18][CH:19]=[CH:20][CH:21]=1)[NH:8][C:9]([C:11]1[CH:12]=[N:13][N:14]([CH3:16])[CH:15]=1)=[O:10])#[N:6]>C(N(CC)CC)C>[O:18]1[CH:19]=[CH:20][CH:21]=[C:17]1[CH:7]([C:5](=[S:1])[NH2:6])[NH:8][C:9]([C:11]1[CH:12]=[N:13][N:14]([CH3:16])[CH:15]=1)=[O:10]

Komponenten

Versuchsvorschrift

Hydrogen sulfide was blown into an ethanol solution containing 1.4 g of the N-(cyano-2-furanylmethyl)-1-methyl-1H-pyrazol-4-carboxamide as obtained in the above process and 0.7 g of triethylamine, for 1 hour, and the whole was stirred for 1 hour under cooling with ice and then for a further 2 hours at room temperature. Afterwards, the crystal formed was taken out by filtration, washed with chloroform and then dried, to obtain 1.1 g of the intended N-[2-furanyl(thiocarbamoyl)-methyl]-1-methyl-1H-pyrazole-4-carboxamide.