Potassium Hydroxide → Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate

HRID 2248746Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2248746
C(SC1SC=CC=1)(=O)C.C([S:13][C:14]1[S:18][C:17]([C:19]([O:21][CH3:22])=[O:20])=[C:16]([OH:23])[C:15]=1[CH3:24])(=O)C.[OH-].[K+]>CO>[OH:23][C:16]1[C:15]([CH3:24])=[C:14]([SH:13])[S:18][C:17]=1[C:19]([O:21][CH3:22])=[O:20]

Komponenten

5

Edukt 3

HCID 14797Potassium HydroxideHCID 13133366Thiophene-2-thiol, S-acetyl-HCID 54710754Methyl 5-acetylthio-3-hydroxy-4-methylthiophene-2-carboxylate

Produkt 1

HCID 54684845Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

The acetylthiothiophene of (f) above (10 mmol) was added to 30 ml of 1M potassium hydroxide in methanol. After acidification of the mixture, the mercapto thiophene was obtained, recrystallising from hexane, m.p. 86°-88° C.

Quellen und Nachweise

ORD-Eintrag
ord-7076ab0dd12c417cb940f3f574dd7eb8
Quelldatensatz
uspto-grants-1991_08
Patentnummer
US05041461

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