2-Morpholinoethylamine → HCID 69277562, Verbindung

HRID 2251158Notizen

Reaktionsgleichung

[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][N:7]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][CH:11]=[C:12]([C:17](O)=[O:18])[CH:13]=3)[C:8]2=[O:20])=[CH:4][CH:3]=1.[O:23]1[CH2:28][CH2:27][N:26]([CH2:29][CH2:30][NH2:31])[CH2:25][CH2:24]1>>[Cl-:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][CH:11]=[C:12]([C:17]([NH:31][CH2:30][CH2:29][NH+:26]4[CH2:27][CH2:28][O:23][CH2:24][CH2:25]4)=[O:18])[CH:13]=3)[C:8]2=[O:20])=[CH:21][CH:22]=1

Komponenten

Edukt 2

HCID 4082852-Morpholinoethylamine

HCID 9079397HCID 9079397, Verbindung

Produkt 1

HCID 69277562HCID 69277562, Verbindung

Versuchsvorschrift

2-(4-chloro-benzyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-carboxylic acid (100 mg, 0.316 mmol) and 2-morpholinoethane amine (103 μL, 0.792 mmol) were reacted with each other. Target compound in the amount of 122 mg (83%) was obtained by following the procedure described in Example 1.

Aufarbeitung

customTarget compound in the amount of 122 mg (83%) was obtained

Quellen und Nachweise

ORD-Eintrag: ord-613e111145ba4d8b94c9897646792e6c
Quelldatensatz: uspto-grants-2008_01
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07319098B2

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