5-Bromo-1-indanone → 1-methyl-5-(1-oxo-2,3-dihydro-1H-inden-5-yl)-1H-pyrrole-2-carbonitrile
Reaktionsgleichung
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[O:11])[CH2:6][CH2:5]2.[CH3:12][N:13]1[CH:17]=[CH:16][CH:15]=[C:14]1[C:18]#[N:19]>>[CH3:12][N:13]1[C:17]([C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[C:7](=[O:11])[CH2:6][CH2:5]3)=[CH:16][CH:15]=[C:14]1[C:18]#[N:19]Komponenten
3
Versuchsvorschrift
The title compound was prepared from 5-bromo-1-indanone and 1-methyl-2-cyanopyrrole according to the coupling procedure as described in example 1. MS (ESI) m/z 237; HRMS: calcd for C15H12N2O+H+, 237.1022; found (ESI, [M+H]+), 237.1003; Anal. Calcd for C15H12N2O: C, 76.25; H, 5.12; N, 11.86. Found: C, 75.99; H, 4.92; N, 11.80.
Quellen und Nachweise
- ORD-Eintrag
- ord-50db46f81c9c4906b8de4e8456125267
- Quelldatensatz
- uspto-grants-2008_01