1-Chloroethyl chloroformate → 2-[(3-Methylphenyl)methyl]morpholine
Reaktionsgleichung
C([N:8]1[CH2:13][CH2:12][O:11][CH:10]([CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[CH:16]=2)[CH2:9]1)C1C=CC=CC=1.C(N1CCO[C@H](CC2C=CC=C(C=CC3C=NC=CC=3)C=2)C1)(OC(C)(C)C)=O.ClC(OC(Cl)C)=O>>[CH3:21][C:17]1[CH:16]=[C:15]([CH:20]=[CH:19][CH:18]=1)[CH2:14][CH:10]1[O:11][CH2:12][CH2:13][NH:8][CH2:9]1Komponenten
4
Versuchsvorschrift
Example 76 was prepared as described for example 27, but using N-benzyl-2-(3-methylbenzyl)-morpholine, intermediate (a) and 1-chloroethyl chloroformate and was isolated as a colorless oil (38.6 mg).
Aufarbeitung
- customExample 76 was prepared
Quellen und Nachweise
- ORD-Eintrag
- ord-b171d6b7b08a403f9e20084daf63a2c2
- Quelldatensatz
- uspto-grants-2008_01
- Patentnummer
- US07323466B2
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