3,4-Dimethoxytoluene → 3,4-Dimethoxy-6-(10-acetyloxydecanoyl)toluene

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

In 50 ml of dichloroethane were dissolved 11.51 g (0.05 mole) of 10-acetyloxydecanoic acid and 14.39 g (0.06 mole) of dichloroacetic anhydride. To the resulting solution were added 9.89 g (0.065 mole) of 3,4-dimethoxytoluene and 0.71 g of boron trifluoridediethyl ether complex and the resulting mixture was then stirred at 75° C. for 5 hours. After completion of the reaction, the reaction solution was cooled and washed successively with water, 5% aqueous sodium carbonate solution and water. The organic layer was dried over anhydrous magnesium sulfate and then concentrated under reduced pressure to obtain 15.3 g of 3,4-dimethoxy-6-(10-acetyloxydecanoyl)toluene.

Herkunft & Nachweise