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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 22546Erstellt: 24. Oktober 2026

5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine → Fadrozole

https://huagongshe.com/de/reaction/22546

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridineHCID 15294718—
EduktHCID 178418361HCID 178418361—
KatalysatorPalladiumHCID 23938—
LösungsmittelEthyl AcetateHCID 8857—
ProduktFadrozoleHCID 59693—

Reaktionsschritte

A solution of 1.6 g of 5-(p-cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine in 50 ml of ethyl acetate is hydrogenated at atmospheric pressure with 0.2 g of 5% palladium on charcoal until the theoretical uptake of hydrogen is complete. The catalyst is filtered, and the solvent evaporated to yield the title compound, m.p. 117°-118°.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05428160
Quelldatensatzuspto-grants-1995_06
ORD IDord-876dfb1f07c84d42a9f8c445f8faa829
Quellennotizuspto-grants-1995_06