Trifluoroacetic acid → 2-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

Reaktionsgleichung

[F:1][C:2]([F:32])([F:31])[C:3]1[N:8]=[C:7]2[CH2:9][N:10](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[CH2:11][C:6]2=[CH:5][CH:4]=1.FC(F)(F)C(O)=O>>[F:32][C:2]([F:1])([F:31])[C:3]1[N:8]=[C:7]2[CH2:9][NH:10][CH2:11][C:6]2=[CH:5][CH:4]=1

Komponenten

Edukt 2

HCID 6422Trifluoroacetic acid

HCID 57753660HCID 57753660, Verbindung

Produkt 1

HCID 569562252-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

Versuchsvorschrift

Prepared in analogy to Example A2(c) from 2-Trifluoromethyl-6-trityl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine and trifluoroacetic acid. Light yellow solid. MS (m/e): 189.3 ([M+H+, 100%).

Quellen und Nachweise

ORD-Eintrag: ord-a3b7407082784464b2e15ba76a9dabca
Quelldatensatz: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07557114B2

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