4-Bromoisoquinolin-5-amine → HCID 53921682, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]([Br:12])=[CH:5][N:6]=[CH:7]2.[CH2:13]([CH:19]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[C:20](O)=[S:21])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>>[Br:12][C:4]1[C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:20](=[S:21])[CH:19]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:7]=[N:6][CH:5]=1Komponenten
3
Versuchsvorschrift
5-Amino-4-bromoisoquinoline (prepared according to the process described by Gordon et. al., J. Het. Chem., 4, 410 (1967)) was coupled with 2-hexylthiodecanoic acid (prepared by the procedures described in Examples 1 and 3) using the procedure described in Example 25 to give the title compound.
Aufarbeitung
- customprepared by the procedures
Quellen und Nachweise
- ORD-Eintrag
- ord-2d1b637ece4f43649041f6d0bf3916a4
- Quelldatensatz
- uspto-grants-1997_08