1,2-Dibromoethane → HCID 22905874, Verbindung

HRID 2257251Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2257251
[Br:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[C:4]([C:9]([CH3:12])([CH3:11])[CH3:10])[C:3]=1[OH:13].[Br:14][CH2:15][CH2:16]Br.C([O-])([O-])=O.[K+].[K+]>CC(C)=O>[Br:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[C:4]([C:9]([CH3:10])([CH3:12])[CH3:11])[C:3]=1[O:13][CH2:16][CH2:15][Br:14]

Komponenten

5

Edukt 3

HCID 78391,2-DibromoethaneHCID 11430Potassium CarbonateHCID 719757AKOS BBS-00008108

Produkt 1

HCID 22905874HCID 22905874, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

To a solution of 2,4-dibromo-6-tert-butylphenol (5.00 g, 16.2 mmol) in acetone (70 mL) is added 1,2-dibromoethane (2.80 mL, 32.5 mmol) and K2CO3 (6.70 g, 48.7 mmol). The mixture is heated at reflux for 14 h, and then is filtered and evaporated. The residue is purified by chromatography over SiO2 eluting with hexanes. The resulting oil is distilled to give 1,5-dibromo-(2-bromoethoxy)-3-tert-butylbenzene as a pale yellow oil.

Aufarbeitung

  1. temperatureThe mixture is heated
  2. temperatureat reflux for 14 h
  3. filtrationis filtered
  4. customevaporated
  5. customThe residue is purified by chromatography over SiO2 eluting with hexanes
  6. distillationThe resulting oil is distilled

Quellen und Nachweise

ORD-Eintrag
ord-0d5c9bdccbd14d19ba2bc61a53154bc0
Quelldatensatz
uspto-grants-1997_08
Patentnummer
US05656661

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