2-(4-Hydroxyphenyl)-5-octylpyrimidine → HCID 21225402, Verbindung
Reaktionsgleichung
[CH2:1]([C:9]1[CH:10]=[N:11][C:12]([C:15]2[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=2)=[N:13][CH:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[F:22][C:23]([F:54])([C:50]([F:53])([F:52])[F:51])[C:24]([F:49])([F:48])[C:25]([F:47])([F:46])[O:26][C:27]([F:45])([F:44])[C:28]([F:43])([F:42])[O:29][C:30]([F:41])([F:40])[CH2:31][O:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]Br>>[CH2:1]([C:9]1[CH:14]=[N:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][O:32][CH2:31][C:30]([O:29][C:28]([F:42])([F:43])[C:27]([F:44])([F:45])[O:26][C:25]([F:46])([F:47])[C:24]([F:48])([F:49])[C:23]([F:22])([F:54])[C:50]([F:52])([F:53])[F:51])([F:41])[F:40])=[CH:17][CH:16]=2)=[N:11][CH:10]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]Komponenten
3
Versuchsvorschrift
The title compound was prepared essentially as in Example 1 by combining 5-octyl-2-(4-hydroxyphenyl)pyrimidine (1.01 g, 3.55 mmol) and 6-(2-(2-(nonafluorobutoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)-1-bromohexane (2.4 g, 4.03 mmol; prepared by combining 1,6-dibromohexane and 2-(2-(nonafluorobutoxy)tetrafluoroethoxy)-2,2-difluoroethanol). The resulting crude product was isolated and further purified essentially as described in Example 3, eluting with 1 vol. % ethyl acetate/toluene