8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide → 8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide, hydrochloride
Reaktionsgleichung
[Cl:1][C:2]1[CH:29]=[CH:28][C:5]2[O:6][C:7]3[CH:27]=[CH:26][CH:25]=[CH:24][C:8]=3[CH2:9][N:10]([C:11]([NH:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]3[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=3)=[O:12])[C:4]=2[CH:3]=1.Cl.CO>CO>[ClH:1].[Cl:1][C:2]1[CH:29]=[CH:28][C:5]2[O:6][C:7]3[CH:27]=[CH:26][CH:25]=[CH:24][C:8]=3[CH2:9][N:10]([C:11]([NH:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]3[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=3)=[O:12])[C:4]=2[CH:3]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
By the method described in Example 16, the title compound of Example 24 (0.82 g, 2.0 mmol) in 40 mL of MeOH was treated with 2N HCl/MeOH (5 mL) to produce 0.25 g of the title product.