HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
ethyl 1-methyl-1H-indole-2-carboxylate → N,1-Dimethyl-5-fluoro-1H-indole-2-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | ethyl 1-methyl-1H-indole-2-carboxylate | HCID 143368 | — |
| Edukt | Ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate | HCID 10775338 | — |
| Produkt | N,1-Dimethyl-5-fluoro-1H-indole-2-carboxamide | HCID 22593743 | 68% |
Reaktionsschritte
According to the procedure of Preparation 1(b), except substituting ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate for the ethyl 1-methyl-1H-indole-2-carboxylate, the title compound (2.1 g, 68%) was prepared as a white solid: MS (ES) m/e 207 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07557125B2 |
| Quelldatensatz | uspto-grants-2009_07 |
| ORD ID | ord-5937838202174a5190a842483394e586 |
| Quellennotiz | uspto-grants-2009_07 |