HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → Buspirone Hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Buspirone | HCID 2477 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | Buspirone Hydrochloride | HCID 36431 | — |
Reaktionsschritte
treating the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione base with hydrogen chloride in ethanol or isopropanol under stirring at a temperature between 15° C. and 40° C. and isolating the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione hydrochloride melting at 188°-191° C., or
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05473072 |
| Quelldatensatz | uspto-grants-1995_12 |
| ORD ID | ord-189f02ab06be41aeab1ce79215069bca |
| Quellennotiz | uspto-grants-1995_12 |