Methyl Palmitate → N-(2,3-dihydroxypropyl)-N-hexadecylhexadecanamide

HRID 2260087Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2260087
[OH:1][CH:2]([CH2:21][OH:22])[CH2:3][NH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[OH-].[K+].[C:25]([O:42]C)(=O)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]>>[OH:1][CH:2]([CH2:21][OH:22])[CH2:3][N:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:25](=[O:42])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]

Komponenten

4

Edukt 3

HCID 8181Methyl PalmitateHCID 14797Potassium HydroxideHCID 1110073-(Hexadecylamino)propane-1,2-diol

Produkt 1

HCID 15825474N-(2,3-dihydroxypropyl)-N-hexadecylhexadecanamide

Versuchsvorschrift

N-(2,3-dihydroxypropyl)-N-hexadecylamine (0.40 g, 0.0013 mole) and potassium hydroxide (0.01 g, 0.18 mmole) were heated to 85° C. under vacuum. Methyl palmitate (0.343 g, 0.0013 mole) was heated to melt and added dropwise to the reaction. The reaction was heated under vacuum for 6 hours. A waxy off-white solid was obtained. The waxy solid was recrystalized from hot hexane (yield=0.4 g).

Aufarbeitung

  1. additionadded dropwise to the reaction
  2. temperatureThe reaction was heated under vacuum for 6 hours
  3. customA waxy off-white solid was obtained
  4. customThe waxy solid was recrystalized from hot hexane (yield=0.4 g)

Quellen und Nachweise

ORD-Eintrag
ord-f73249bdb3a74b9a820d288babe2b712
Quelldatensatz
uspto-grants-1995_12
Patentnummer
US05476671

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