6,11-Dihydro-2-methyldibenz[b,e]-oxepin-11-carboxylic acid → 6,11-Dihydro-N-(2,6-diisopropyl-4-thiocyanatophenyl)-2-methyldibenz[b,e]oxepin-11-carboxamide

HRID 2260589

Reaktionsgleichung

Reaktionsgleichung von HRID 2260589
[CH3:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][CH2:7][C:8]3[CH:17]=[CH:16][CH:15]=[CH:14][C:9]=3[CH:10]([C:11](O)=[O:12])[C:4]=2[CH:3]=1.[CH:20]([C:23]1[CH:29]=[C:28]([S:30][C:31]#[N:32])[CH:27]=[C:26]([CH:33]([CH3:35])[CH3:34])[C:24]=1[NH2:25])([CH3:22])[CH3:21]>>[CH:20]([C:23]1[CH:29]=[C:28]([S:30][C:31]#[N:32])[CH:27]=[C:26]([CH:33]([CH3:35])[CH3:34])[C:24]=1[NH:25][C:11]([CH:10]1[C:9]2[CH:14]=[CH:15][CH:16]=[CH:17][C:8]=2[CH2:7][O:6][C:5]2[CH:18]=[CH:19][C:2]([CH3:1])=[CH:3][C:4]1=2)=[O:12])([CH3:22])[CH3:21]

Komponenten

3

Edukt 2

HCID 101063426,11-Dihydro-2-methyldibenz[b,e]-oxepin-11-carboxylic acidHCID 189984884-Amino-3,5-di(propan-2-yl)phenyl thiocyanate

Produkt 1

HCID 189984846,11-Dihydro-N-(2,6-diisopropyl-4-thiocyanatophenyl)-2-methyldibenz[b,e]oxepin-11-carboxamideAusbeute 78,6 %

Versuchsvorschrift

The similar procedures as in Example 1 were repeated except using 1.12 g of Compound A and 1.24 g of 2,6-diisopropyl-4-thiocyanatoaniline in place of aniline to obtain 1.63 g of Compound 31.

Quellen und Nachweise

ORD-Eintrag
ord-22e0d0af7369422387a48d9ec6e913a1
Quelldatensatz
uspto-grants-1995_12
Patentnummer
US05478835

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