4-(Dimethylamino)quinazoline-6-carbaldehyde → 5-[[4-(Dimethylamino)quinazolin-6-yl]methylidene]-2-imino-1,3-thiazolidin-4-one

HRID 2261129

Reaktionsgleichung

Reaktionsgleichung von HRID 2261129
[CH3:1][N:2]([CH3:15])[C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([CH:13]=O)[CH:11]=2)[N:6]=[CH:5][N:4]=1.[NH:16]=[C:17]1[NH:21][C:20](=[O:22])[CH2:19][S:18]1>>[NH:16]=[C:17]1[NH:21][C:20](=[O:22])[C:19](=[CH:13][C:10]2[CH:11]=[C:12]3[C:7](=[CH:8][CH:9]=2)[N:6]=[CH:5][N:4]=[C:3]3[N:2]([CH3:15])[CH3:1])[S:18]1

Komponenten

3

Edukt 2

HCID 574696434-(Dimethylamino)quinazoline-6-carbaldehyde2×HCID 1357419972-Aminothiazolinone HCl

Produkt 1

HCID 1527589305-[[4-(Dimethylamino)quinazolin-6-yl]methylidene]-2-imino-1,3-thiazolidin-4-one

Versuchsvorschrift

Following the general method as outlined in Example 1, starting from 4-piperidine-quinazoline-6-carbaldehyde (intermediate 14) and 2-imino-1,3-thiazolidin-4-one, the title compound was obtained.

Quellen und Nachweise

ORD-Eintrag
ord-7796b2709bf24bc1a3c00daa103a756d
Quelldatensatz
uspto-grants-2010_12
Patentnummer
US07846925B2

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