Thionyl Chloride → 5-(Chloromethyl)-3-methoxy-1,2-oxazole

HRID 2261363Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2261363
[CH3:1][O:2][C:3]1[CH:7]=[C:6]([CH2:8]O)[O:5][N:4]=1.S(Cl)([Cl:12])=O>ClCCl>[Cl:12][CH2:8][C:6]1[O:5][N:4]=[C:3]([O:2][CH3:1])[CH:7]=1

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 106782583-Methoxy-5-isoxazolemethanol

Produkt 1

HCID 100805435-(Chloromethyl)-3-methoxy-1,2-oxazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

1.55 g of (3-methoxyisoxazol-5-yl)methanol was dissolved in 30 ml of dichloromethane, and 2 ml of thionyl chloride was then added. The mixture was stirred at room temperature for 1 hour. The reaction mixture was concentrated under reduced pressure to obtain 1.30 g of 5-(chloromethyl)-3-methoxyisoxazole.

Aufarbeitung

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-34a66417c5ec4ca4a731d514b97630a2
Quelldatensatz
uspto-grants-2010_12
Patentnummer
US07846956B2

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