HCID 1475693, Verbindung → 2-Ethylthio-1-methylimidazole-5-carbaldehyde

HRID 2261365Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2261365
[CH2:1]([S:3][C:4]1[N:5]([CH3:11])[C:6]([CH2:9][OH:10])=[CH:7][N:8]=1)[CH3:2]>O1CCOCC1.[O-2].[O-2].[Mn+4]>[CH2:1]([S:3][C:4]1[N:5]([CH3:11])[C:6]([CH:9]=[O:10])=[CH:7][N:8]=1)[CH3:2]

Komponenten

4

Edukt 1

HCID 1475693HCID 1475693, Verbindung

Produkt 1

HCID 27633102-Ethylthio-1-methylimidazole-5-carbaldehydeAusbeute 94,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418406HCID 178418406, VerbindungKatalysatorHCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

5.50 g of (2-ethylthio-1-methylimidazol-5-yl)methanol was dissolved in 100 ml of 1,4-dioxane, and 24.34 g of manganese dioxide was then added. The mixture was stirred and heated under reflux for 7 hours. The reaction mixture was cooled to room temperature and then filtered through Celite®. The filtrate was concentrated under reduced pressure to obtain 5.13 g of 2-ethylthio-1-methylimidazole-5-carbaldehyde.

Aufarbeitung

  1. temperatureheated
  2. temperatureunder reflux for 7 hours
  3. filtrationfiltered through Celite®
  4. concentrationThe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-a469f03287e14c9f8f12f0e332c2e101
Quelldatensatz
uspto-grants-2010_12
Patentnummer
US07846956B2

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