Selenium → 7-Methoxy-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one

HRID 226265

Reaktionsgleichung

[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:16][CH2:15][C:10]3=[N:11][CH:12]=[CH:13][CH:14]=[C:9]3[C:8](=[O:17])[C:7]=2[CH:18]=1.[Se]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:16]=[CH:15][C:10]3=[N:11][CH:12]=[CH:13][CH:14]=[C:9]3[C:8](=[O:17])[C:7]=2[CH:18]=1

Komponenten

Reaktionsbedingungen

Temperatur: 120 °C

Versuchsvorschrift

A mixture of 2.3 g (9.6 mmol) of the product from Example 23 step 4, 1.85 g (16.6 mmol) of selenium dioxyde and 5 ml of pyridine is stirred at 120° C. for 6 hr. The whole is poured into excess petroleum ether and the solution is evaporated giving 0.55 g (24%) of enough pure title product as to prosecute with the synthesis.

Aufarbeitung

customthe solution is evaporated

Quellen und Nachweise

ORD-Eintrag: ord-927970835fe54928acc167750afbfec8
Quelldatensatz: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07557212B2

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