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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2263961Erstellt: 26. Oktober 2026

Phosgene → rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-[2-ethoxy-4-(1-hydroxy-1-methyl-ethyl)-phenyl]-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride

https://huagongshe.com/reaction/2263961

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPhosgeneHCID 6371—
EduktHCID 17754634HCID 17754634—
LösungsmittelTriethylamineHCID 8471—
Produktrac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-[2-ethoxy-4-(1-hydroxy-1-methyl-ethyl)-phenyl]-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 73408763—

Reaktionsschritte

In a manner analogous to the method described in example 3, rac-2-{4-[(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-2-yl]-3-ethoxy-phenyl}-propan-2-ol was reacted with phosgene in the presence of triethylamine to give the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07851626B2
Quelldatensatzuspto-grants-2010_12
ORD IDord-448455874a4441018cd0acac35b5c9c1
Quellennotizuspto-grants-2010_12