HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phosgene → rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-[2-ethoxy-4-(1-hydroxy-1-methyl-ethyl)-phenyl]-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phosgene | HCID 6371 | — |
| Edukt | HCID 17754634 | HCID 17754634 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-[2-ethoxy-4-(1-hydroxy-1-methyl-ethyl)-phenyl]-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 73408763 | — |
Reaktionsschritte
In a manner analogous to the method described in example 3, rac-2-{4-[(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-2-yl]-3-ethoxy-phenyl}-propan-2-ol was reacted with phosgene in the presence of triethylamine to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07851626B2 |
| Quelldatensatz | uspto-grants-2010_12 |
| ORD ID | ord-448455874a4441018cd0acac35b5c9c1 |
| Quellennotiz | uspto-grants-2010_12 |