Phosgene → rac-(4S,5R)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Phosgene	HCID 6371	—
Edukt	rac-(4S,5R)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole	HCID 68685099	—
Lösungsmittel	Triethylamine	HCID 8471	—
Produkt	rac-(4S,5R)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride	HCID 73408764	—

Reaktionsschritte

In a manner analogous to the method described in example 3, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole was reacted with phosgene in the presence of triethylamine to give the title compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07851626B2
Quelldatensatz	uspto-grants-2010_12
ORD ID	ord-8c57ab80e14e42d287ceb005d905ce04
Quellennotiz	uspto-grants-2010_12