Ammonia → HCID 59595967, Verbindung
Reaktionsgleichung
CO[C:3]1[C:8]([N+:9]([O-:11])=[O:10])=[CH:7][CH:6]=[C:5]([C:12]2[O:13][CH:14]=[CH:15][N:16]=2)[N:4]=1.[NH3:17]>>[N+:9]([C:8]1[C:3]([NH2:17])=[N:4][C:5]([C:12]2[O:13][CH:14]=[CH:15][N:16]=2)=[CH:6][CH:7]=1)([O-:11])=[O:10]Komponenten
3
Reaktionsbedingungen
- Temperatur
- 100 °C
Versuchsvorschrift
A suspension of 2-methoxy-3-nitro-6-(1,3-oxazol-2-yl)pyridine (0.187 g, 0.85 mmol) in aqueous ammonia (32%, 5 mL) was heated in a sealed tube to 100° C. with stirring. After 2.5 hours the mixture was cooled and the precipitate was filtered and washed with water and then dried in vacuo to give the title compound (0.134 g, 77%) as a yellow solid.
Aufarbeitung
- temperatureAfter 2.5 hours the mixture was cooled
- filtrationthe precipitate was filtered
- washwashed with water
- customdried in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-bade95ccfb0740ec8e7645ffadde844b
- Quelldatensatz
- uspto-grants-2010_12
- Patentnummer
- US07855202B2
Notizen zur Reaktion
Wird geladen…