Ethyl 3-(4-aminophenyl)acrylate → Ethyl 4-[[3,5-bis(trimethylsilyl)benzoyl]amino]cinnamate
Reaktionsgleichung
[NH2:1][C:2]1[CH:14]=[CH:13][C:5]([CH:6]=[CH:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:4][CH:3]=1.[CH3:15][Si:16]([CH3:44])([CH3:43])[C:17]1[CH:18]=[C:19]([CH:36]=[C:37]([Si:39]([CH3:42])([CH3:41])[CH3:40])[CH:38]=1)[C:20](NC1N=CC(/C=C/C(OCC)=O)=CC=1)=[O:21]>>[CH3:40][Si:39]([CH3:42])([CH3:41])[C:37]1[CH:36]=[C:19]([CH:18]=[C:17]([Si:16]([CH3:44])([CH3:43])[CH3:15])[CH:38]=1)[C:20]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([CH:6]=[CH:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:13][CH:14]=1)=[O:21]Komponenten
3
Versuchsvorschrift
Using BTMB (10.0 g) and ethyl 4-aminocinnamate (8.62 g), Compound 3a (10.3 g, 62%) was obtained as a yellow solid in the same manner as Compound 1b was obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-4635d42b7e51473ea5f01bfead313f22
- Quelldatensatz
- uspto-grants-2010_12