Methyl 2-(4-hydroxypiperidin-1-yl)acetate → (4-Methoxy-piperidin-1-yl)-acetic acid methyl ester

Reaktionsgleichung

COC(=O)C[C@H]1[CH2:10][CH2:9][C@H:8]([O:11][CH3:12])[CH2:7][CH2:6]1.[CH3:14][O:15][C:16](=[O:25])[CH2:17][N:18]1CCC(O)CC1>>[CH3:14][O:15][C:16](=[O:25])[CH2:17][N:18]1[CH2:6][CH2:7][CH:8]([O:11][CH3:12])[CH2:9][CH2:10]1

Komponenten

Edukt 2

HCID 28837753Methyl 2-(4-hydroxypiperidin-1-yl)acetate

HCID 178500707HCID 178500707, Verbindung

Produkt 1

HCID 43216568(4-Methoxy-piperidin-1-yl)-acetic acid methyl ester

Versuchsvorschrift

The title compound can be prepared in accordance with the general method of intermediate B, step 3 from (4-hydroxy-piperidin-1-yl)-acetic acid methyl ester.

Quellen und Nachweise

ORD-Eintrag: ord-68854e0d22e8448581a27d3605761c69
Quelldatensatz: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07858630B2

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