(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester → (S)-2-{3-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy}propionic Acid Methyl Ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester	HCID 66717596	—
Edukt	2-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-3-oxopentanoic Acid Ethyl Ester	HCID 68784675	—
Produkt	(S)-2-{3-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy}propionic Acid Methyl Ester	HCID 68782627	—

Reaktionsschritte

The title compound was prepared by the method of Preparation 65c using 2-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-3-oxopentanoic acid ethyl ester and (S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07858640B2
Quelldatensatz	uspto-grants-2010_12
ORD ID	ord-f1baca9cfb1c442182784ef2555eeb36
Quellennotiz	uspto-grants-2010_12