(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester → (S)-2-[3-(2-chloro-4-cyclobutylcarbamoylbenzyl)-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy]propionic Acid Methyl Ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester	HCID 66717596	—
Edukt	2-(2-chloro-4-cyclobutylcarbamoylbenzyl)-3-oxopentanoic Acid Ethyl Ester	HCID 68782611	—
Produkt	(S)-2-[3-(2-chloro-4-cyclobutylcarbamoylbenzyl)-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy]propionic Acid Methyl Ester	HCID 68784731	—

Reaktionsschritte

The title compound was prepared by the method of Preparation 65c using 2-(2-chloro-4-cyclobutylcarbamoylbenzyl)-3-oxopentanoic acid ethyl ester and (S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07858640B2
Quelldatensatz	uspto-grants-2010_12
ORD ID	ord-28a08cdc21da43d8a37c48fe4c875e78
Quellennotiz	uspto-grants-2010_12