(2H-1,3-benzodioxol-5-yl)boronic acid → 4-(4-Benzo[1,3]dioxol-5-yl-phenoxymethyl)-5-methyl-furan-2-carboxylic acid
Reaktionsgleichung
C[O:2][C:3]([C:5]1[O:6][C:7]([CH3:19])=[C:8]([CH2:10][O:11][C:12]2[CH:17]=[CH:16][C:15](I)=[CH:14][CH:13]=2)[CH:9]=1)=[O:4].[CH2:20]1[O:28][C:27]2[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][C:22]=2[O:21]1>>[O:21]1[C:22]2[CH:23]=[CH:24][C:25]([C:15]3[CH:16]=[CH:17][C:12]([O:11][CH2:10][C:8]4[CH:9]=[C:5]([C:3]([OH:2])=[O:4])[O:6][C:7]=4[CH3:19])=[CH:13][CH:14]=3)=[CH:26][C:27]=2[O:28][CH2:20]1Komponenten
3
Versuchsvorschrift
Compound (28) was prepared from compound (20) and (3,4-methylenedioxyphenyl)-boronic acid by adapting the procedure of Example 24A. LC/MS System B; Rt=1.76 mins, m/z (ES−)=351 (M−H for C20H16O6).
Quellen und Nachweise
- ORD-Eintrag
- ord-eeaf6bbc47a04b9487b1657edd7c0dd6
- Quelldatensatz
- uspto-grants-2010_12