HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,4-Benzodioxan-6-ylamine → N2-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(2-hydro xy-2-phenylethyl)-2,4-pyrimidinediamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,4-Benzodioxan-6-ylamine | HCID 89148 | — |
| Edukt | N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-primidinediamine | HCID 22060334 | — |
| Edukt | 2-chloro-5-fluoro-N4-(2-hydroxy-2-phenylethyl)-4-pyrimidineamine | HCID 22060827 | — |
| Produkt | N2-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(2-hydro xy-2-phenylethyl)-2,4-pyrimidinediamine | HCID 22060669 | — |
Reaktionsschritte
In a manner similar to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine, 2-chloro-5-fluoro-N4-(2-hydroxy-2-phenylethyl)-4-pyrimidineamine and 3,4-ethylenedioxyaniline were reacted to yield N2-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(2-hydroxy-2-phenylethyl)-2,4-pyrimidinediamine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07557210B2 |
| Quelldatensatz | uspto-grants-2009_07 |
| ORD ID | ord-0f20c43f67914c2ab846aa746d95d6eb |
| Quellennotiz | uspto-grants-2009_07 |