HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2',4'-Dihydroxy-3'-propylacetophenone → 2-(3-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)phenylthio) isonicotinonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2',4'-Dihydroxy-3'-propylacetophenone | HCID 2775198 | — |
| Edukt | 2-{[3-(Hydroxymethyl)phenyl]sulfanyl}pyridine-4-carbonitrile | HCID 57355460 | — |
| Produkt | 2-(3-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)phenylthio) isonicotinonitrile | HCID 68535659 | 81,2% |
Reaktionsschritte
Using the method of Preparation 166 using 2-(3-(hydroxymethyl)phenylthio) isonicotinonitrile (1.25 g, 5.15 mmol) and 1-(2,4-dihydroxy-3-propylphenyl)ethanone (1.00 g, 5.15 mmol) affords the title compound (1.75 g, 81%). MS (APCI-neg) m/z (rel intensity): 417 (M−H, 100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07858646B2 |
| Quelldatensatz | uspto-grants-2010_12 |
| ORD ID | ord-b9e7d9d3205d4e9d9b5668444078131f |
| Quellennotiz | uspto-grants-2010_12 |