Cesium carbonate → 3-(1-{[3-(cyclopentylamino)propyl]sulfonyl}-4-piperidinyl)-5-[3-(hydroxymethyl)phenyl]-1H-indole-7-carboxamide

Reaktionsgleichung

N1(CCS(N2CCC(C3[C:25]4[C:20](=[C:21]([C:31](N)=[O:32])[CH:22]=[C:23](C5C=CSC=5)[CH:24]=4)NC=3)CC2)(=O)=O)CCCC1.Br[C:35]1[CH:36]=[C:37]2[C:41](=[C:42]([C:44]([NH2:46])=[O:45])[CH:43]=1)[NH:40][CH:39]=[C:38]2[CH:47]1[CH2:52][CH2:51][N:50]([S:53]([CH2:56][CH2:57][CH2:58][NH:59][CH:60]2[CH2:64][CH2:63][CH2:62][CH2:61]2)(=[O:55])=[O:54])[CH2:49][CH2:48]1.OCC1C=C(B(O)O)C=CC=1.C(=O)([O-])[O-].[Cs+].[Cs+]>C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[CH:60]1([NH:59][CH2:58][CH2:57][CH2:56][S:53]([N:50]2[CH2:49][CH2:48][CH:47]([C:38]3[C:37]4[C:41](=[C:42]([C:44]([NH2:46])=[O:45])[CH:43]=[C:35]([C:25]5[CH:24]=[CH:23][CH:22]=[C:21]([CH2:31][OH:32])[CH:20]=5)[CH:36]=4)[NH:40][CH:39]=3)[CH2:52][CH2:51]2)(=[O:54])=[O:55])[CH2:64][CH2:63][CH2:62][CH2:61]1