Sodium Bicarbonate → HCID 20709190, Verbindung
Reaktionsgleichung
CS[C:3]1[N:11]=[C:10]2[C:6]([N:7]=[CH:8][N:9]2[CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][O:13]2)=[C:5]([NH:18][CH2:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[N:4]=1.O[O:28][S:29]([O-:31])=O.[K+].[C:33](=O)([O-])O.[Na+]>>[CH3:33][S:29]([C:3]1[N:11]=[C:10]2[C:6]([N:7]=[CH:8][N:9]2[CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][O:13]2)=[C:5]([NH:18][CH2:19][CH2:20][C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[N:4]=1)(=[O:31])=[O:28]Komponenten
4
Versuchsvorschrift
The title compound was prepared by a similar method to preparation 8 from 2-(methylsulfanyl)-N-phenethyl-9-tetrahydro-2H-pyran-2-yl-9H-purin-6-amine (16.7 g, 45 mmol) (preparation 42), Oxone (trade mark) (42.0 g, 136 mmol) and solid sodium hydrogen carbonate (20 g, 238 mmol). This gave the title compound (21.4 g) as a white solid. MS: 402 (MH+).
Quellen und Nachweise
- ORD-Eintrag
- ord-176d79a468384ac2908b75aeef046f00
- Quelldatensatz
- uspto-grants-2001_12
- Patentnummer
- US06326359B1
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