3-(2-Amino-4,5-dimethoxyphenyl)-2-methyl-2-propenoic acid ethyl ester → 6,7-Dimethoxy-3-methyl-carbostyril

HRID 2269781Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2269781
C([O:3][C:4](=O)[C:5]([CH3:18])=[CH:6][C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[CH:9][C:8]=1[NH2:17])C>C(O)C>[CH3:14][O:13][C:11]1[CH:12]=[C:7]2[C:8](=[CH:9][C:10]=1[O:15][CH3:16])[NH:17][C:4](=[O:3])[C:5]([CH3:18])=[CH:6]2

Komponenten

3

Edukt 1

HCID 702131123-(2-Amino-4,5-dimethoxyphenyl)-2-methyl-2-propenoic acid ethyl ester

Produkt 1

HCID 183480236,7-Dimethoxy-3-methyl-carbostyrilAusbeute 92 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Into 30 ml of ethyl alcohol, 0.5 g of 3-(2-amino-4,5-dimethoxyphenyl)-2-methyl-2-propenoic acid ethyl ester was dissolved. This solution was irradiated with ultraviolet rays at 365 nm for about 20 hours, and the precipitated crystal was filtered out. This crystal was recrystallized from ethanol, whereby 0.38 g of the aimed compound was obtained (yield: 92%).

Aufarbeitung

  1. customThis solution was irradiated with ultraviolet rays at 365 nm for about 20 hours
  2. filtrationthe precipitated crystal was filtered out
  3. customThis crystal was recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-d163b67745eb45f392d832254474f72a
Quelldatensatz
uspto-grants-2001_12
Patentnummer
US06329546B1

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