HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Amino-2-methylpyridine → 3-(4-Methoxy-3-methyl-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Amino-2-methylpyridine | HCID 243313 | — |
| Edukt | 3-Ethoxy-2-(4-methoxy-3-methyl-benzoyl)-acrylic acid methyl ester | HCID 66878626 | — |
| Lösungsmittel | Diphenyl Ether | HCID 7583 | — |
| Produkt | 3-(4-Methoxy-3-methyl-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one | HCID 57754706 | 56,9% |
Reaktionsschritte
Experimental conditions analogous to those described for Step 1 of Example 1 were used with 0.50 g (1.88 mmol) of 3-ethoxy-2-(4-methoxy-3-methyl-benzoyl)-acrylic acid methyl ester, 0.20 g (1.88 mmol) of 6-Methyl-pyridin-3-ylamine, and 10 mL of diphenyl ether to yield 0.33 g of 3-(4-Methoxy-3-methyl-benzoyl)-6-methyl-1H-[1,5]naphthyridin-4-one.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07557213B2 |
| Quelldatensatz | uspto-grants-2009_07 |
| ORD ID | ord-2b9834e73ab544c49c9d92747a0ce5c9 |
| Quellennotiz | uspto-grants-2009_07 |