3-(2-(Dimethylamino)ethyl)aniline → HCID 68092217, Verbindung
Reaktionsgleichung
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][C:6]([C:12](=[O:14])[CH3:13])=[C:5]2Cl.[CH3:16][N:17]([CH3:27])[CH2:18][CH2:19][C:20]1[CH:21]=[C:22]([CH:24]=[CH:25][CH:26]=1)[NH2:23]>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][C:6]([C:12](=[O:14])[CH3:13])=[C:5]2[NH:23][C:22]1[CH:24]=[CH:25][CH:26]=[C:20]([CH2:19][CH2:18][N:17]([CH3:16])[CH3:27])[CH:21]=1Komponenten
3
Versuchsvorschrift
Following general procedure C, 1-(6-bromo-4-chloroquinolin-3-yl)ethanone (340 mg, 1.20 mmol) was reacted with 3-(2-(dimethylamino)ethyl)aniline (215 mg, 1.31 mmol) to afford the desired product (360 mg, 50%) as a yellow solid: ESI MS m/z 412 [C21H22BrN3O+H]+.
Quellen und Nachweise
- ORD-Eintrag
- ord-5bf41618c7bc4f8aa97350f91c57bd7a
- Quelldatensatz
- uspto-grants-2015_09