Propargylamine → 6,6-Dimethyl-5,6-dihydro-benzo[f]quinoline
Reaktionsgleichung
[CH3:1][C:2]1([CH3:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5][C:4](=O)[CH2:3]1.[CH2:14]([NH2:17])[C:15]#[CH:16]>>[CH3:1][C:2]1([CH3:13])[CH2:3][C:4]2[N:17]=[CH:14][CH:15]=[CH:16][C:5]=2[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:11]1=2Komponenten
3
Versuchsvorschrift
The title compound is prepared from 4,4-dimethyl-3,4-dihydro-1H-naphthalen-2-one and propargylamine following a procedure analogous to that described in Step 1 of Intermediates 1 and 2. Yield: 49% of theory; LC (method 1): tR=2.40 min; Mass spectrum (ESI+): m/z=210 [M+H]+.
Quellen und Nachweise
- ORD-Eintrag
- ord-048dcf048dbb42a49d5ff4051d10bb9d
- Quelldatensatz
- uspto-grants-2015_09
- Patentnummer
- US09120769B2
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