2-Bromoethyl methyl ether → HCID 11370925, Verbindung

HRID 227272Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 227272
[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH:9]([C:12]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[NH:14][CH:13]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].Br[CH2:22][CH2:23][O:24][CH3:25]>>[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH:9]([C:12]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[N:14]([CH2:22][CH2:23][O:24][CH3:25])[CH:13]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Komponenten

3

Edukt 2

HCID 809722-Bromoethyl methyl etherHCID 11380267Ethyl 4-(1H-indol-3-yl)piperidine-1-carboxylate

Produkt 1

HCID 11370925HCID 11370925, VerbindungAusbeute 98,4 %

Versuchsvorschrift

This compound was prepared following the procedure described in example 1, part D, starting with 5.5 g (0.02 mol) of 4-(1H-indol-3-yl)-piperidine-carboxylic acid ethyl ester and 2.3 ml (0.0233 mol) of 1-bromo-2-methoxyethane. The reaction mixture was stirred at room temperature for 24 h and after standard work-up, 6.5 g (98% of yield) of 4-[1-(2-methoxyethyl)-1H-indol-3-yl]-piperidine-1-carboxylic acid ethyl ester were obtained.

Aufarbeitung

  1. customThis compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-0578854bc59f471d9d12d939f9133cc1
Quelldatensatz
uspto-grants-2009_07
Patentnummer
US07560471B2

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