HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → 2-(2-Oxopyrrolidin-1-yl)ethyl methanesulfonate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Methanesulfonyl chloride | HCID 31297 | — |
| Edukt | 1-(2-Hydroxyethyl)-2-pyrrolidinone | HCID 76980 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 2-(2-Oxopyrrolidin-1-yl)ethyl methanesulfonate | HCID 44627116 | — |
Reaktionsschritte
The 1-(2-hydroxyethyl)-2-pyrrolidinone (Aldrich, 0.16 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07560481B2 |
| Quelldatensatz | uspto-grants-2009_07 |
| ORD ID | ord-d816450421db4ac6abf27b635fdd7572 |
| Quellennotiz | uspto-grants-2009_07 |