HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methyl-5-(2-hydroxyethyl)thiazole → 5-Thiazoleethanol, 4-methyl-, 5-methanesulfonate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methyl-5-(2-hydroxyethyl)thiazole | HCID 1136 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Methanesulfonyl chloride | HCID 31297 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 5-Thiazoleethanol, 4-methyl-, 5-methanesulfonate | HCID 10104926 | — |
Reaktionsschritte
The 4-methyl-5-thiazole ethanol (Aldrich, 0.18 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07560481B2 |
| Quelldatensatz | uspto-grants-2009_07 |
| ORD ID | ord-e3ac47f2f60440cba9fad8d793c7a4e0 |
| Quellennotiz | uspto-grants-2009_07 |