4-Piperidinol, 1-methyl- → 6,6-Dimethyl-8-(1-methyl-piperidin-4-yloxy)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Reaktionsgleichung
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17](=[O:18])[C:16]3[C:15]4[C:10](=[CH:11][C:12]([C:19]#[N:20])=[CH:13][CH:14]=4)[NH:9][C:8]=3[C:7]([CH3:22])([CH3:21])[C:6]=2[CH:23]=1.[CH3:24][N:25]1[CH2:30][CH2:29][CH:28](O)[CH2:27][CH2:26]1>>[CH3:22][C:7]1([CH3:21])[C:8]2[NH:9][C:10]3[C:15](=[CH:14][CH:13]=[C:12]([C:19]#[N:20])[CH:11]=3)[C:16]=2[C:17](=[O:18])[C:5]2[CH:4]=[CH:3][C:2]([O:1][CH:28]3[CH2:29][CH2:30][N:25]([CH3:24])[CH2:26][CH2:27]3)=[CH:23][C:6]1=2Komponenten
3
Versuchsvorschrift
Under the same conditions as the method for synthesizing Compound A7-1, the title compound was prepared from Compound A6 and 1-methylpiperidin-4-ol.
Aufarbeitung
- customUnder the same conditions as the method for synthesizing Compound A7-1
Quellen und Nachweise
- ORD-Eintrag
- ord-71fa18f048c848f9881a1121324bb780
- Quelldatensatz
- uspto-grants-2015_09
- Patentnummer
- US09126931B2
Notizen zur Reaktion
Wird geladen…