2-Tert-butylpropanedioic acid → 4-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester

HRID 2275273Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2275273
[CH3:1][O:2][C:3]1[N:8]=[C:7]([C:9]([CH3:14])([CH3:13])[C:10]([OH:12])=O)[CH:6]=[CH:5][CH:4]=1.C([CH:19]([C:23]([OH:25])=[O:24])C(O)=O)(C)(C)C>>[C:9]([O:25][C:23](=[O:24])[CH2:19][C:10](=[O:12])[C:9]([C:7]1[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[N:8]=1)([CH3:14])[CH3:13])([CH3:13])([CH3:10])[CH3:7]

Komponenten

3

Edukt 2

HCID 2427522-Tert-butylpropanedioic acidHCID 668349942-(6-Methoxypyridin-2-yl)-2-methylpropanoic acid

Produkt 1

HCID 668345394-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester

Versuchsvorschrift

The title compound was synthesized from 2-(6-methoxy-pyridin-2-yl)-2-methyl-propionic acid and mono-tert-butyl malonic acid according to the method used for the synthesis of Compound PR4. The resultant was used for the next step without further purification.

Aufarbeitung

  1. customused for the synthesis of Compound PR4
  2. customThe resultant was used for the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-c8c729664cae41a19f9f987239398a62
Quelldatensatz
uspto-grants-2015_09
Patentnummer
US09126931B2

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