Glycine methyl ester hydrochloride → HCID 57712377, Verbindung
Reaktionsgleichung
[CH:1]1([C:6]([C:8]2[CH:13]=[C:12]([CH3:14])[CH:11]=[CH:10][C:9]=2[NH:15][C:16]([NH:18][C:19]2[S:20][C:21]([CH:24]=O)=[CH:22][N:23]=2)=[O:17])=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[CH3:27][O:28][C:29](=[O:32])[CH2:30][NH2:31]>>[CH3:27][O:28][C:29](=[O:32])[CH2:30][NH:31][CH2:24][C:21]1[S:20][C:19]([NH:18][C:16]([NH:15][C:9]2[CH:10]=[CH:11][C:12]([CH3:14])=[CH:13][C:8]=2[C:6]([CH:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[O:7])=[O:17])=[N:23][CH:22]=1Komponenten
3
Versuchsvorschrift
({2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-ylmethyl}-amino)-acetic acid methyl ester (38 mg, 45%) was prepared from 1-(2-cyclopentanecarbonyl-4-methyl-phenyl)-3-(5-formyl-thiazol-2-yl)-urea (0.072 g, 0.2 mmol) and glycine methyl ester hydrochloride following the general procedure O.
Quellen und Nachweise
- ORD-Eintrag
- ord-06bb5bfddecc47bdb29b731c311c99f7
- Quelldatensatz
- uspto-grants-2015_09