HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → N-{2-(acetylamino)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethy}-2-(trifluoromethyl)benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 2-(Trifluoromethyl)benzoic acid | HCID 9899 | — |
| Edukt | 4-(4,6-Dimethoxy[1.3.5]triazin-2-yl)-4-methylmorpholinium chloride hydrate | HCID 23149411 | — |
| Edukt | N-{2-amino-1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}acetamide trifluoroacetate | HCID 86612330 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | N-{2-(acetylamino)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethy}-2-(trifluoromethyl)benzamide | HCID 86612329 | — |
Reaktionsschritte
108 mg of N-{2-amino-1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}acetamide trifluoroacetate (0.0003 mol), 76 mg of 2-(trifluoromethyl)benzoic acid (0.0003 mol)), 83 mg of 4-(4,6-dimethoxy[1.3.5]triazin-2-yl)-4-methylmorpholinium chloride hydrate (0.0003 mol) and 41 μL of triethylamine (0.0003 mol) are stirred in 3 mL of ethanol at room temperature overnight.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07560567B2 |
| Quelldatensatz | uspto-grants-2009_07 |
| ORD ID | ord-289122d3fd244f40bcd2f2a126f0925d |
| Quellennotiz | uspto-grants-2009_07 |