Bromomethylcyclopropane → N-((2S)-1-((2-(4-(cyclopropylmethoxy)phenyl) [1,3]thiazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide
Reaktionsgleichung
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:9][C:10]3[CH:15]=[C:14]([O:16][CH2:17][C@@H:18]([NH:20][C:21](=[O:23])[CH3:22])[CH3:19])[N:13]=[CH:12][C:11]=3[N:24]=2)=[CH:4][CH:3]=1.Br[CH2:26][CH:27]1[CH2:29][CH2:28]1>>[CH:27]1([CH2:26][O:1][C:2]2[CH:3]=[CH:4][C:5]([C:8]3[S:9][C:10]4[CH:15]=[C:14]([O:16][CH2:17][C@@H:18]([NH:20][C:21](=[O:23])[CH3:22])[CH3:19])[N:13]=[CH:12][C:11]=4[N:24]=3)=[CH:6][CH:7]=2)[CH2:29][CH2:28]1Komponenten
3
Versuchsvorschrift
Using N-((2S)-1-((2-(4-hydroxyphenyl)[1,3]thiazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide and (bromomethyl)cyclopropane, and in the same manner as in Example 5, the title compound was obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-ce1d7a274c10453e9add66dbb282fece
- Quelldatensatz