1-Benzyl-2,5-dimethylpiperazine → trans-1-Benzyl-5-methyl-2-phenyl-piperazine

HRID 2279173Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2279173
[CH2:1]([N:8]1[CH2:13][CH:12]([CH3:14])[NH:11][CH2:10][CH:9]1[CH3:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC(N1[CH2:28][C@@H:27]([C:29]2C=CC=[CH:31][CH:30]=2)NC[C@@H]1C)=O)(C)(C)C>>[CH2:1]([N:8]1[CH2:13][C@@H:12]([CH3:14])[NH:11][CH2:10][C@@H:9]1[C:15]1[CH:31]=[CH:30][CH:29]=[CH:27][CH:28]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 219941881-Benzyl-2,5-dimethylpiperazineHCID 40639181trans-2-Methyl-5-phenyl-piperazine-1-carboxylic acid tert-butyl ester

Produkt 1

HCID 86680328trans-1-Benzyl-5-methyl-2-phenyl-piperazine

Versuchsvorschrift

trans-1-Benzyl-5-methyl-2-phenyl-piperazine was prepared in analogy to the preparation of benzyl-2,5-dimethyl-piperazine (see above) starting form trans-2-methyl-5-phenyl-piperazine-1-carboxylic acid tert-butyl ester.

Quellen und Nachweise

ORD-Eintrag
ord-b45b945054c64cce9007660b615d3744
Quelldatensatz
uspto-grants-2015_09
Patentnummer
US09133181B2

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