4-bromo-1-(3-hydroxypropyl)-1H-pyrazole-5-carbonitrile → 3-amino-6-[5-cyano-1-(3-hydroxypropyl)-1H-pyrazol-4-yl]-N-methylpyridine-2-carboxamide
Reaktionsgleichung
NC1C=CC(C2C=NN(CCCO)C=2)=CC=1C(N(CC)CC)=O.[NH2:24][C:25]1[C:26]([C:40]([NH:42][CH3:43])=[O:41])=[N:27][C:28](B2OC(C)(C)C(C)(C)O2)=[CH:29][CH:30]=1.Br[C:45]1[CH:46]=[N:47][N:48]([CH2:52][CH2:53][CH2:54][OH:55])[C:49]=1[C:50]#[N:51]>>[NH2:24][C:25]1[C:26]([C:40]([NH:42][CH3:43])=[O:41])=[N:27][C:28]([C:45]2[CH:46]=[N:47][N:48]([CH2:52][CH2:53][CH2:54][OH:55])[C:49]=2[C:50]#[N:51])=[CH:29][CH:30]=1Komponenten
4
