1-cyclopentyl-N-methylpiperidin-4-amine → 2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopentyl)piperidine-4-yl)-N-methylacetamide

HRID 2280931

Reaktionsgleichung

Reaktionsgleichung von HRID 2280931
C(OC([NH:8][C:9]1[C:10]([CH3:21])=[N:11][C:12]([O:16][CH2:17][C:18]([OH:20])=O)=[N:13][C:14]=1[CH3:15])=O)(C)(C)C.[CH:22]1([N:27]2[CH2:32][CH2:31][CH:30]([NH:33][CH3:34])[CH2:29][CH2:28]2)[CH2:26][CH2:25][CH2:24][CH2:23]1>>[NH2:8][C:9]1[C:14]([CH3:15])=[N:13][C:12]([O:16][CH2:17][C:18]([N:33]([CH:30]2[CH2:31][CH2:32][N:27]([CH:22]3[CH2:23][CH2:24][CH2:25][CH2:26]3)[CH2:28][CH2:29]2)[CH3:34])=[O:20])=[N:11][C:10]=1[CH3:21]

Komponenten

3

Edukt 2

HCID 433153691-cyclopentyl-N-methylpiperidin-4-amineHCID 593361682-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)acetic acid

Produkt 1

HCID 593362002-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopentyl)piperidine-4-yl)-N-methylacetamide

Versuchsvorschrift

The title compound was synthesized from Compound 9 and 1-cyclopentyl-N-methylpiperidine-4-amine in the same manner as in Example 64.

Quellen und Nachweise

ORD-Eintrag
ord-e0870bcda8d44f5b8c5760f332e13eae
Quelldatensatz
uspto-grants-2015_09
Patentnummer
US09139559B2

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